
Cosmelan® Depigmentation Program in Sheffield
Target Pigmentation at Its Source with the World’s Leading Depigmentation Treatment
At The Skin Firm, we are proud to offer the Cosmelan® Depigmentation Peel—a globally recognised treatment for reducing pigmentation, melasma, sunspots, and post-inflammatory hyperpigmentation. As Sheffield’s trusted depigmentation specialists, we combine clinical expertise with prescription-strength skincare to deliver transformative results.
This professional-grade peel, developed by mesoestetic®, is the gold standard for reducing excess melanin production and restoring an even, radiant complexion. Ideal for all skin tones, Cosmelan offers visible improvement with just 2 weeks of downtime—making it the preferred choice for clients seeking long-term clarity.

What is Cosmelan and How Does It Work?
Cosmelan is a dual-action depigmentation system. It works by:
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Inhibiting tyrosinase, the key enzyme responsible for melanin production
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Exfoliating existing pigmented skin layers
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Preventing the reappearance of future dark spots
The program includes:
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A skin preparation phase
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An in-clinic application of the Cosmelan 1 mask,
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A 6-month regulated homecare phase using Cosmelan 2 kits.
Continued use of recommended Mesoestetic products is essential to maintain long-term results.
Up to 95% reduction in visible pigmentation
Benefits of the Cosmelan Peel
Suitable for all skin phototypes (Fitzpatrick I–VI)
Effective on melasma, sun damage, and PIH
Non-invasive with no need for lasers or injectables
Scientifically backed and used in over 85 countries
A 2020 study published in the Journal of Clinical and Aesthetic Dermatology found that Cosmelan achieved a significant reduction in melasma within four weeks, with continued improvement at 12 weeks when paired with homecare
RESULTS

What Skin Conditions Does Cosmelan Treat?
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Melasma (hormonal pigmentation)
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Sun spots and age spots
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Post-inflammatory hyperpigmentation (PIH)
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Uneven skin tone
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Dullness caused by sun exposure or ageing
The Cosmelan Peel is not a generic facial - it is a medical-grade depigmentation protocol, prescribed and monitored by a qualified skin specialist. At The Skin Firm, all treatments are conducted under the care of Dr Naren, ensuring the highest standard of safety and efficacy.
Your Cosmelan Treatment Journey at The Skin Firm
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Comprehensive Consultation: We begin with an in-depth skin assessment to confirm suitability and set realistic expectations.
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In-Clinic Application: Cosmelan 1 is applied to the skin and left in place for a prescribed period, depending on your skin type and concern.
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Homecare Phase: You’ll continue treatment at home with Cosmelan 2, Hydra-vital Factor K, and Melan Recovery cream to maintain and enhance results.
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Ongoing Review: We provide detailed aftercare guidance and review your skin’s progress throughout the depigmentation journey.
FAQs
Why Choose The Skin Firm for Cosmelan?
✔ Depigmentation Specialists in Sheffield
✔ Doctor-Led Clinic – Medical supervision from consultation through aftercare
✔ Authorised Cosmelan Provider – Using genuine mesoestetic® products
✔ Structured Aftercare & Support
✔ 5-Star Reputation
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